On April 19, 1828, a Negro of Dr. Tyler's, while digging clay in the doctor's backyard in Frederick, found a box of money containing about $2,000.
On April 19, 1865, Frederick officially mourned the death of President Abraham Lincoln.
On April 19, 1885, Robert E. Delaplaine, who would become publisher of The News and The Frederick Post, and president of The Great Southern Printing and Manufacturing Company, was born. He died August 15, 1955, at Johns Hopkins Hospital in Baltimore.
On April 19, 1901, Charles T. "Cephus" Overs was hanged at the Frederick County Jail on West South Street for the murder of Frank T. Donaldson near Monrovia on October 31, 1900.
On April 19, 1921, The International Order of Old Fellows decided to build a large retirement and nursing home in Frederick on the Gittinger Farm on North Market Street extended. The Banner School now occupies the facilities built by the Odd Fellows.
On April 19, 1971, officials at St. Joseph's College in Emmitsburg announced the school would be closed in 1973.
On April 19, 1990, the first Frederick Keys baseball game was played at Harry Grove Stadium. The Keys play in a Single A league.