On January 21, 1781, Thomas Johnson, as a member of the Maryland House of Delegates, introduced a bill authorizing the confiscation of all British property in the state.
On January 21, 1877, at a company meeting, the Independent Hose Company No. 1 agreed to purchase a steam fire engine from the La France Company. This engine was nicknamed “Romeo” when it was delivered. On November 23, 1880, a fire at the Frederick City Petroleum Works, on East Patrick Street near Water Street, resulted in the loss of "Romeo." It fell off a bridge into Carroll Creek. The engine was replaced by "Juliet" on March 18, 1881.
On January 21, 1894, Helen Smith, who lived most of her life at Old Braddock west of Frederick and who was a renowned local artist, was born.
On January 21, 1906, the First Baptist Church of Brunswick was organized.